UPDATE: 6:04PM - Yuma Regional Medical Center has confirmed that one of their doctors has died in the plane crash earlier today in Santee, California. 

"We are deeply sad to hear news of a plane owned by local cardiologist Dr. Sugata Das, which crashed near Santee. As an outstanding cardiologist and dedicated family man, Dr. Das leaves a lasting legacy. We extend our prayers and support to his family, colleagues, and friends during this difficult time." - Statement from Dr. Bharat Magu, Chief Medical Officer, YRMC

The plane crash in a Santee, California near San Diego has killed a UPS driver. Earlier today, the company released a statement saying they are "heartbroken by the loss" of their employee.  Images of the scene show a UPS delivery truck severely burned.  At least two other people have been reported dead and at least two homes have been considered destroyed.  It's reported that the plane was coming from Yuma when it went down.